BioNTech-Pfizer vaccine: common adverse events in Spain

As of December 31, 2022, around 14,398 cases of pyrexia (fever) had been reported after administering the Pfizer/BioNTech vaccine against COVID-19 in Spain. Pyrexia was the most common adverse event recorded, followed by headache and myalgia. By that time, approximately 44,280 adverse events were identified following the administration of the Comirnaty Original vaccine (Pfizer/BioNTech) in Spain.

Most common adverse events reported after receiving the BioNTech-Pfizer (Comirnaty) vaccine against COVID-19 in Spain as of December 31, 2022

Characteristic	Number of cases
Pyrexia	14,398
Headache	9,288
Myalgia	6,636
Pain in the vaccination area	5,680
Discomfort	5,432
Fatigue	3,332
Lymphadenopathy	3,098
Sickness	2,773
Chills	2,472
Asthenia	2,417

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Release date

January 2023

More information

Region

Spain

Survey time period

as of December 31, 2022

Supplementary notes

Includes any kind of adverse event notified after receiving the coronavirus (COVID-19) vaccine. Adverse events are not to be interpreted as induced by the vaccine until a casual relationship is confirmed.

As of December 31, 2022, a total of 67,263,416 doses of the BioNTech-Pfizer (Comirnaty original) vaccine had been administered in Spain.

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