
Leading causes of death in the United States 2018-2021
From 2018 to 2021, heart disease and cancer accounted for the highest share of deaths in the United States. In 2020 and 2021, COVID-19 became the third leading cause of death accounting for around 12 percent of all deaths in 2021. This statistic shows the distribution of the 10 leading causes of death in the United States in 2018, 2019, 2020, and 2021.