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2020 list of top U.S. biotech and pharmaceutical companies based on revenue

Based on revenues latest available as of 2020, Johnson & Johnson was the leading pharmaceutical company in the United States. The firm annually generates over 80 billion U.S. dollars, which is around 30 billion U.S. dollars more than the next ranked company, Pfizer. However, Johnson & Johnson's total revenue includes also sales from their medical device and consumer health divisions, while Pfizer is a pure-play pharmaceutical company.

Branded and generic drugs: What are the differences?

Patented products marketed by pharmaceutical companies are referred to as branded. The protection of the patent means that the company, which has spent a large amount of money researching and developing the product, can exclusively sell the drug – often at a high price to recoup its investment. Once the patent expires, other companies may produce generic versions of the product, which contain the same key ingredients.

2020 ranking of top 10 U.S. biotech and pharmaceutical companies based on total revenue*

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Release date

October 2020



Survey time period

as of September 2020

Supplementary notes

* Including only companies with a headquarter in the United States. Revenues are global totals.
Date released is the date figures were accessed. The source gives no information if data is based on financial or calendar years, or MATs, nor about used exchange rates.
FT classifies Cardinal Health as a pharmaceutical company, although it is more a diversified health services and (pharmaceutical) distribution company than a pharmaceutical manufacturer as the other ranked companies. Thus, it is not included in this ranking.

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Statistics on "U.S. pharmaceutical industry"

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