The most successful Marvel movie to date is by far 'Avengers: Endgame', which generated 357.12 million U.S. dollars in domestic box office revenue in its opening weekend alone. Second was 'Spider-Man: No Way Home', which made 260.14 million during its first weekend in movie theaters.
Opening weekend box office revenue of Marvel movies in North America as of May 2023 (in million U.S. dollars)
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Topics

the-numbers.com. (May 8, 2023). Opening weekend box office revenue of Marvel movies in North America as of May 2023 (in million U.S. dollars) [Graph]. In Statista. Retrieved September 30, 2023, from https://www.statista.com/statistics/879373/marvel-movies-opening-weekend/
the-numbers.com. "Opening weekend box office revenue of Marvel movies in North America as of May 2023 (in million U.S. dollars)." Chart. May 8, 2023. Statista. Accessed September 30, 2023. https://www.statista.com/statistics/879373/marvel-movies-opening-weekend/
the-numbers.com. (2023). Opening weekend box office revenue of Marvel movies in North America as of May 2023 (in million U.S. dollars). Statista. Statista Inc.. Accessed: September 30, 2023. https://www.statista.com/statistics/879373/marvel-movies-opening-weekend/
the-numbers.com. "Opening Weekend Box Office Revenue of Marvel Movies in North America as of May 2023 (in Million U.S. Dollars)." Statista, Statista Inc., 8 May 2023, https://www.statista.com/statistics/879373/marvel-movies-opening-weekend/
the-numbers.com, Opening weekend box office revenue of Marvel movies in North America as of May 2023 (in million U.S. dollars) Statista, https://www.statista.com/statistics/879373/marvel-movies-opening-weekend/ (last visited September 30, 2023)
Opening weekend box office revenue of Marvel movies in North America as of May 2023 (in million U.S. dollars) [Graph], the-numbers.com, May 8, 2023. [Online]. Available: https://www.statista.com/statistics/879373/marvel-movies-opening-weekend/