Clinical trials

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Statista dossier about clinical research

This dossier presents key facts and figures about clinical trials worldwide, with a focus on the United States. Clinical trials are also known as Phase I to IV within the research, development, and approval process for new drugs, medical devices, or procedures. This document gives you an overview about health R&D in general, number of clinical studies, success rates, costs, and many more.

Table of contents

  • 1. R&D overview
    • Total global pharmaceutical R&D spending 2010-2024

    • Industry sectors - expenditure on research and development 2012-2016

    • Top pharmaceutical R&D projects based on net present value May 2018

    • Research and development expenditure: U.S. pharmaceutical industry 1995-2017

    • Research and development in European pharmaceutical industry by country 2016

    • Total clinical research funding by National Institutes for Health 2013-2018

  • 2. Top R&D companies
    • Global top pharmaceutical companies based on R&D spending 2024

    • Top 50 global pharmaceutical and biotech companies by R&D intensity in 2016/2017

    • Top pharmaceutical companies in R&D spending growth 2016-2017

    • Roche: participation of patients in clinical trials 2009-2017

    • Leading global contract research organizations based on revenue 2017

  • 3. Clinical studies
    • Comparison between the complexity of clinical trials 2001-2015

    • Increase in clinical trials' complexity 2001-2015

    • Number of registered clinical studies by location worldwide 2018

    • Percent of registered clinical studies worldwide by location 2018

    • Share of recruiting clinical studies worldwide by location 2018

    • Total number of registered clinical studies worldwide since 2000

    • Total number of registered clinical studies with posted results worldwide 2009-2018

  • 4. Participation
    • Clinical trial enrollment by select country and region 2016

    • Top clinical trial participant countries 2015-2016, by number

    • Top clinical trial participant countries worldwide 2015-16, by share

    • Clinical trial participants U.S. vs. rest of world by therapy area 2016

    • Clinical trial participants gender share worldwide 2015-16, by geographic location

    • Clinical trial participants ethnicity share worldwide 2015-16, by geographic location

  • 5. Costs and market
    • Pharmaceuticals: cost of drug development in the U.S. since 1975

    • Total R&D costs of select cancer drugs 2017

    • Market share of clinical trials worldwide by segment

    • Clinical CRO market size worldwide 2011-2020

    • Size of U.S. healthcare CRO market 2016-2022 by type

    • Size of total U.S. clinical trial supplies market 2016-2025

  • 6. Success rates
    • U.S. drug development Phase success rates 2006-2015

    • U.S. drug development Phase II success rates 2006-2015, by disease area

    • U.S. drug development Phase III success rates from 2006 to 2015, by disease area

    • U.S. development Phase success rates for oncology and non oncology drugs 2006-2015

    • U.S. drug development Phase success rates, by drug classification 2006-2015

    • U.S. development phase success rates for drugs with and without biomarkers 2006-2015

  • 7. Approvals, launches, setbacks
    • Pharmaceutical industry - number of new substances 1992-2017

    • Number of novel drugs approved annually by CDER 2008-2017

    • Key measurements of U.S. CDER drug approvals in 2017

    • FDA first premarket approvals for medtech products granted 2005-2017

    • Projection of top 2018 pharma and biotech launches by revenue 2022

    • Number of unsuccessful Alzheimer’s drugs in development in the U.S. 1998-2017

    • Unsuccessful attempts and new drugs for cancer types 1998-2014

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