Top 20 most abused prescription drugs in the U.S. in 2016, by revenue (in million U.S. dollars)

20 most abused prescription drugs in the U.S. by revenue 2016 This statistic shows the 20 most abused pharmaceutical drugs in the United States in 2016, sorted by revenue. According to the data, methlyphenidate HCl was the most abused pharmaceutical drug with 2016 sales reaching over two billion U.S. dollars.
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Revenue in million U.S. dollars
Methylphenidate HCl2,073
OxyContin (oxycondone HCl controled-release)1,390
Celecoxib1,246
Burenorphine and naloxone1,026
Suboxone (buprenorphine and naloxone)935
Concerta (methylphenidate HCl)863
Celebrex (celecoxib capsule)733
Fentanyl560
Zolpidem tartrate491
Celecox (celecoxib)434.5
Adderall XR (amphetamine/dextroamphetamine)363.8
Sertraline HCL349
Hydromorphone HCl316
Ambien (zolpidem tartrate)304
Zoloft (sertraline HCl)304
Methylphenidate ER288
Duragesic (fentanyl transdermal system)288
Ritalin/Focalin (methylphenidate HCl)282
Subsys (fentanyl sublingual spray)242.3
Morphine suflate132
Revenue in million U.S. dollars
Methylphenidate HCl2,073
OxyContin (oxycondone HCl controled-release)1,390
Celecoxib1,246
Burenorphine and naloxone1,026
Suboxone (buprenorphine and naloxone)935
Concerta (methylphenidate HCl)863
Celebrex (celecoxib capsule)733
Fentanyl560
Zolpidem tartrate491
Celecox (celecoxib)434.5
Adderall XR (amphetamine/dextroamphetamine)363.8
Sertraline HCL349
Hydromorphone HCl316
Ambien (zolpidem tartrate)304
Zoloft (sertraline HCl)304
Methylphenidate ER288
Duragesic (fentanyl transdermal system)288
Ritalin/Focalin (methylphenidate HCl)282
Subsys (fentanyl sublingual spray)242.3
Morphine suflate132
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Description Source More information
This statistic shows the 20 most abused pharmaceutical drugs in the United States in 2016, sorted by revenue. According to the data, methlyphenidate HCl was the most abused pharmaceutical drug with 2016 sales reaching over two billion U.S. dollars.
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Release date
September 2017
Region
United States
Survey time period
2016

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