The opioid epidemic in the U.S. - Statistics & Facts

Key insights

Number of opioid overdose deaths in the U.S. in 2021
Death rate due to opioid overdose in the U.S. in 2021 (per 100,000 population)
State with the highest opioid overdose death rate
West Virginia

Editor’s Picks Current statistics on this topic

Related topics



Recommended statistics

U.S. overview

Prescription opioids



Overview of deaths from opioids

Costs due to opioid abuse and death

Further reportsGet the best reports to understand your industry


Get in touch with us. We are happy to help.
Statista Locations
Contact Meredith Alda
Meredith Alda
Sales Manager– Contact (United States)

Mon - Fri, 9am - 6pm (EST)

Contact Yolanda Mega
Yolanda Mega
Operations Manager– Contact (Asia)

Mon - Fri, 9am - 5pm (SGT)

Contact Kisara Mizuno
Kisara Mizuno
Senior Business Development Manager– Contact (Asia)

Mon - Fri, 10:00am - 6:00pm (JST)

Contact Lodovica Biagi
Lodovica Biagi
Director of Operations– Contact (Europe)

Mon - Fri, 9:30am - 5pm (GMT)

Contact Carolina Dulin
Carolina Dulin
Group Director - LATAM– Contact (Latin America)

Mon - Fri, 9am - 6pm (EST)