
Opioid use in the U.S. - Statistics & Facts
Key insights
- Share of U.S. adults who thought opioid addiction was the most important health issue facing the U.S. in 2023
- 6%

Detailed statistics
Most important health issues facing the U.S. according to U.S. adults 2023
- Share of those aged 12 years and older who found it easy to obtain heroin
- 14%

Detailed statistics
Individuals finding it easy to obtain heroin in the U.S. 2002-2021
- Lifetime odds of dying from opioids in the U.S.
- 1 in 58

Detailed statistics
Lifetime odds of dying from select causes in the U.S. in 2021
Editor’s Picks Current statistics on this topic
Current statistics on this topic
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U.S. overview
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- Basic Statistic Share of U.S. adults who thought select health issues were a crisis 2022
- Basic Statistic Public perception on opioid abuse and addiction in the U.S. 2020-2022
- Basic Statistic Most important health issues facing the U.S. according to U.S. adults 2023
- Basic Statistic Americans opinion on main public health threat in the U.S. in 2023
- Basic Statistic Anxiety among U.S. adults in regards to select aspects of life from 2020 to 2023
- Basic Statistic Share of U.S. adults with opioid addiction in family as of 2023, by community type
- Basic Statistic Share of U.S. adults with opioid addiction in family as of 2023, by race/ethnicity
- Basic Statistic Share of U.S. adults who supported select policies to reduce drug overdoses in 2023
- Premium Statistic Lifetime odds of dying from select causes in the U.S. in 2021
- Premium Statistic Deaths from drug overdose in the U.S. 2020-2021, by drug
U.S. overview
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Basic Statistic
Share of U.S. adults who thought select health issues were a crisis 2022
Share of U.S. adults who thought select health issues were a crisis 2022
Percentage of adults in the United States who thought select health issues were a crisis in the country as of 2022
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Basic Statistic
Public perception on opioid abuse and addiction in the U.S. 2020-2022
Public perception on opioid abuse and addiction in the U.S. 2020-2022
Percentage of U.S. adults who agree that opioid abuse and addiction is a major problem from 2020 to 2022
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Basic Statistic
Most important health issues facing the U.S. according to U.S. adults 2023
Most important health issues facing the U.S. according to U.S. adults 2023
Percentage of U.S. adults that thought select health issues were most important for the U.S. as of 2019 and 2023
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Basic Statistic
Americans opinion on main public health threat in the U.S. in 2023
Americans opinion on main public health threat in the U.S. in 2023
Of the following, what do you think is the number one threat to the American public health at this moment?
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Basic Statistic
Anxiety among U.S. adults in regards to select aspects of life from 2020 to 2023
Anxiety among U.S. adults in regards to select aspects of life from 2020 to 2023
Percentage of U.S. adults that were anxious about select aspects of their lives in 2020, 2021, and 2023*
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Basic Statistic
Share of U.S. adults with opioid addiction in family as of 2023, by community type
Share of U.S. adults with opioid addiction in family as of 2023, by community type
Share of adults in the U.S. who reported they or someone in their family had been addicted to opioids at some point in their lifetime as of 2023, by community type
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Basic Statistic
Share of U.S. adults with opioid addiction in family as of 2023, by race/ethnicity
Share of U.S. adults with opioid addiction in family as of 2023, by race/ethnicity
Share of adults in the U.S. who reported they or someone in their family had been addicted to opioids at some point in their lifetime as of 2023, by race and ethnicity
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Basic Statistic
Share of U.S. adults who supported select policies to reduce drug overdoses in 2023
Share of U.S. adults who supported select policies to reduce drug overdoses in 2023
Percentage of adults who supported or opposed select policies to reduce drug overdoses in the United States as of 2023
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Lifetime odds of dying from select causes in the U.S. in 2021
Lifetime odds of dying from select causes in the U.S. in 2021
Lifetime odds of dying for select causes in the United States in 2021
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Deaths from drug overdose in the U.S. 2020-2021, by drug
Deaths from drug overdose in the U.S. 2020-2021, by drug
Number of drug overdose deaths in the U.S. in 2020 and 2021, by drug
Prescription opioids
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- Premium Statistic Number of opioid prescriptions U.S. 2006-2020
- Premium Statistic Prescription opioid dispensing rates in the U.S. 2006-2020
- Basic Statistic Non medical use of Rx pain relievers over the last year in the U.S. 2002-2021
- Premium Statistic Number of prescription opioid overdose deaths U.S. 1999-2021
- Premium Statistic Prescription opioid overdose U.S. death rate 1999-2021
- Basic Statistic Death rate due to prescription opioid overdose U.S. 1999-2021, by gender
- Basic Statistic Death rate due to prescription opioid overdose U.S. 1999-2021, by race/ethnicity
Prescription opioids
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Premium Statistic
Number of opioid prescriptions U.S. 2006-2020
Number of opioid prescriptions U.S. 2006-2020
Number of annual opioid prescriptions in the U.S. from 2006 to 2020
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Premium Statistic
Prescription opioid dispensing rates in the U.S. 2006-2020
Prescription opioid dispensing rates in the U.S. 2006-2020
Rate of prescription opioids dispensed in the United States from 2006 to 2020 (per 100 persons)
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Basic Statistic
Non medical use of Rx pain relievers over the last year in the U.S. 2002-2021
Non medical use of Rx pain relievers over the last year in the U.S. 2002-2021
Number of people in the U.S. who used prescription opioids for non medical purposes from 2002 to 2021* (in millions)
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Number of prescription opioid overdose deaths U.S. 1999-2021
Number of prescription opioid overdose deaths U.S. 1999-2021
Number of overdose deaths from prescription opioids in the U.S. from 1999 to 2021
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Prescription opioid overdose U.S. death rate 1999-2021
Prescription opioid overdose U.S. death rate 1999-2021
Prescription opioid overdose death rate in the U.S. from 1999 to 2021 (per 100,000 population)
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Basic Statistic
Death rate due to prescription opioid overdose U.S. 1999-2021, by gender
Death rate due to prescription opioid overdose U.S. 1999-2021, by gender
U.S. death rate from prescription opioid overdose from 1999 to 2021, by gender (per 100,000 population)
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Basic Statistic
Death rate due to prescription opioid overdose U.S. 1999-2021, by race/ethnicity
Death rate due to prescription opioid overdose U.S. 1999-2021, by race/ethnicity
U.S. death rate from prescription opioid overdose from 1999 to 2021, by race/ethnicity (per 100,000 population)
Heroin
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- Premium Statistic Individuals starting to consume heroin in the U.S. 2002-2021
- Premium Statistic Individuals who consumed heroin during past year in the U.S. 2002-2021
- Basic Statistic Individuals who consumed heroin during the past year in the U.S. 2002-2021, by age
- Basic Statistic Heroin dependence or abuse within past year in the U.S. 2002-2021, by age
- Premium Statistic Number of heroin overdose deaths U.S. 1999-2021
- Premium Statistic Heroin overdose U.S. death rate 1999-2021
- Premium Statistic Overdose death rate from heroin U.S. 2020, by state
Heroin
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Individuals starting to consume heroin in the U.S. 2002-2021
Individuals starting to consume heroin in the U.S. 2002-2021
Number of individuals taking heroin for the first time in the United States from 2002 to 2021* (in 1,000)
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Individuals who consumed heroin during past year in the U.S. 2002-2021
Individuals who consumed heroin during past year in the U.S. 2002-2021
Number of individuals who consumed heroin during the past year in the United States from 2002 to 2021 (in 1,000)
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Basic Statistic
Individuals who consumed heroin during the past year in the U.S. 2002-2021, by age
Individuals who consumed heroin during the past year in the U.S. 2002-2021, by age
Number of individuals who consumed heroin during the past year in the United States from 2002 to 2021, by age (in 1,000)
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Basic Statistic
Heroin dependence or abuse within past year in the U.S. 2002-2021, by age
Heroin dependence or abuse within past year in the U.S. 2002-2021, by age
Number of individuals with a heroin dependence or abuse during the past year in the United States from 2002 to 2021, by age (in 1,000)
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Number of heroin overdose deaths U.S. 1999-2021
Number of heroin overdose deaths U.S. 1999-2021
Number of overdose deaths from heroin in the U.S. from 1999 to 2021
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Heroin overdose U.S. death rate 1999-2021
Heroin overdose U.S. death rate 1999-2021
Death rate from heroin overdose in the U.S. from 1999 to 2021 (per 100,000 population)
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Overdose death rate from heroin U.S. 2020, by state
Overdose death rate from heroin U.S. 2020, by state
Heroin overdose death rate in the United States in 2020, by state (per 100,000 population)
Fentanyl
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- Basic Statistic Number of fentanyl overdose deaths U.S. 1999-2021
- Basic Statistic Number of fentanyl overdose deaths U.S. 1999-2021, by gender
- Premium Statistic Number of U.S. deaths from illicit fentanyls in 2020, by age group
- Basic Statistic Number of U.S. deaths from illicit fentanyls in 2020, by region and gender
- Basic Statistic Rate of overdose deaths involving fentanyl in the U.S. 1999-2021
- Basic Statistic Rate of overdose deaths involving fentanyl in the U.S. 1999-2021, by gender
- Premium Statistic Rate of overdose deaths involving fentanyl in the U.S. 1999-2021, by race/ethnicity
Fentanyl
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Basic Statistic
Number of fentanyl overdose deaths U.S. 1999-2021
Number of fentanyl overdose deaths U.S. 1999-2021
Number of overdose deaths from fentanyl in the U.S. from 1999 to 2021
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Basic Statistic
Number of fentanyl overdose deaths U.S. 1999-2021, by gender
Number of fentanyl overdose deaths U.S. 1999-2021, by gender
Number of overdose deaths from fentanyl in the U.S. from 1999 to 2021, by gender
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Number of U.S. deaths from illicit fentanyls in 2020, by age group
Number of U.S. deaths from illicit fentanyls in 2020, by age group
Number of drug overdose deaths that involved illicitly manufactured fentanyls in the U.S. in 2020, by age group
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Basic Statistic
Number of U.S. deaths from illicit fentanyls in 2020, by region and gender
Number of U.S. deaths from illicit fentanyls in 2020, by region and gender
Number of drug overdose deaths that involved illicitly manufactured fentanyls in the U.S. in 2020, by region and gender
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Basic Statistic
Rate of overdose deaths involving fentanyl in the U.S. 1999-2021
Rate of overdose deaths involving fentanyl in the U.S. 1999-2021
Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2021 (per 100,000 population)
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Basic Statistic
Rate of overdose deaths involving fentanyl in the U.S. 1999-2021, by gender
Rate of overdose deaths involving fentanyl in the U.S. 1999-2021, by gender
Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2021, by gender (per 100,000 population)
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Rate of overdose deaths involving fentanyl in the U.S. 1999-2021, by race/ethnicity
Rate of overdose deaths involving fentanyl in the U.S. 1999-2021, by race/ethnicity
Rate of drug overdose deaths involving fentanyl in the U.S. from 1999 to 2021, by race/ethnicity (per 100,000 population)
Overview of deaths from opioids
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- Premium Statistic U.S. opioid overdose deaths number from 1999 to 2021
- Premium Statistic U.S. opioid overdose death rate from 1999 to 2021
- Premium Statistic Opioid drug overdose male death rates in the U.S. 1999-2021
- Premium Statistic Opioid drug overdose female death rates in the U.S. 1999-2021
- Premium Statistic U.S. opioid drug overdose death rates from 1999-2021, by race/ethnicity
- Basic Statistic Share of deaths from opioid overdose in the U.S. in 2021, by age
- Premium Statistic Death rate from opioid overdose in the U.S. in 2021, by state
Overview of deaths from opioids
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U.S. opioid overdose deaths number from 1999 to 2021
U.S. opioid overdose deaths number from 1999 to 2021
Number of opioid overdose deaths in the U.S. from 1999 to 2021
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Premium Statistic
U.S. opioid overdose death rate from 1999 to 2021
U.S. opioid overdose death rate from 1999 to 2021
Death rate due to opioid overdose in the U.S. from 1999 to 2021 (per 100,000 population)
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Premium Statistic
Opioid drug overdose male death rates in the U.S. 1999-2021
Opioid drug overdose male death rates in the U.S. 1999-2021
Death rate from drug poisonings involving opioids among men in the U.S. from 1999 to 2021 (per 100,000 population)
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Opioid drug overdose female death rates in the U.S. 1999-2021
Opioid drug overdose female death rates in the U.S. 1999-2021
Death rate from drug poisonings involving opioids among women in the U.S. from 1999 to 2021 (per 100,000 population)
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U.S. opioid drug overdose death rates from 1999-2021, by race/ethnicity
U.S. opioid drug overdose death rates from 1999-2021, by race/ethnicity
Death rate from drug poisonings involving opioids in the U.S. from 1999 to 2021, by race/ethnicity (per 100,000 population)
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Basic Statistic
Share of deaths from opioid overdose in the U.S. in 2021, by age
Share of deaths from opioid overdose in the U.S. in 2021, by age
Distribution of opioid overdose deaths in the U.S. in 2021, by age
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Death rate from opioid overdose in the U.S. in 2021, by state
Death rate from opioid overdose in the U.S. in 2021, by state
Opioid overdose death rate in the United States in 2021, by state (per 100,000 population)
Costs due to opioid abuse and death
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- Premium Statistic Nonfatal costs of opioid use disorder in the U.S. in 2017, by type of cost
- Premium Statistic Cost of opioid use disorder in the U.S. in 2017, by state
- Basic Statistic Per capita cost of opioid use disorder in the U.S. in 2017, by state
- Basic Statistic Costs of fatal opioid overdose in the U.S. in 2017, by type of cost
- Basic Statistic Cost of fatal opioid overdose in the U.S. in 2017, by state
- Basic Statistic Fatal opioid overdose per capita costs in the U.S. in 2017, by state
Costs due to opioid abuse and death
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Premium Statistic
Nonfatal costs of opioid use disorder in the U.S. in 2017, by type of cost
Nonfatal costs of opioid use disorder in the U.S. in 2017, by type of cost
Estimated nonfatal costs of opioid use disorder in the United States in 2017, by type of cost (in million U.S. dollars)
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Cost of opioid use disorder in the U.S. in 2017, by state
Cost of opioid use disorder in the U.S. in 2017, by state
Cost of opioid use disorder in the United States in 2017, by state* (in million U.S. dollars)
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Basic Statistic
Per capita cost of opioid use disorder in the U.S. in 2017, by state
Per capita cost of opioid use disorder in the U.S. in 2017, by state
Per capita cost of opioid use disorder in the United States in 2017, by state* (in U.S. dollars)
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Basic Statistic
Costs of fatal opioid overdose in the U.S. in 2017, by type of cost
Costs of fatal opioid overdose in the U.S. in 2017, by type of cost
Estimated costs of fatal opioid overdose in the United States in 2017, by type of cost (in million U.S. dollars)
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Basic Statistic
Cost of fatal opioid overdose in the U.S. in 2017, by state
Cost of fatal opioid overdose in the U.S. in 2017, by state
Cost of fatal opioid overdose in the United States in 2017, by state* (in million U.S. dollars)
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Basic Statistic
Fatal opioid overdose per capita costs in the U.S. in 2017, by state
Fatal opioid overdose per capita costs in the U.S. in 2017, by state
Per capita cost of fatal opioid overdose in the United States in 2017, by state* (in U.S. dollars)
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