Try our corporate solution for free!
(212) 419-8286

U.S. drug overdose deaths number from 1999 to 2018, by gender

From 1999 to 2018, the number of drug overdose deaths among U.S. females increased from 5,591 in 1999 to over 22 thousand in 2018. Globally, drug use is a general problem. In 2017, it was estimated that over half of all adults globally had used illegal drugs in their lifetime. As of 2016, there were an estimated 275 million global drug consumers and 30.5 million drug addicts. Despite the large number of drug users globally, the U.S. still shares the largest burden of alcohol and substance use disorders. According to recent data, over 5 percent of the global burden of substance use and alcohol use disorders were attributable to the U.S.

Opioid use in the United States

Among all demographics, drug overdose deaths continue to rise in the U.S. Opioids are the most commonly reported substance in drug-related deaths. The number of drug-related deaths in the U.S. due to opioids has dramatically increased in recent years. In 2017, President Donald Trump declared a national emergency over the opioid crisis in the U.S. Since then, there have been joint efforts among various governmental departments to address the opioid crisis through education and outreach.

Substance use treatment

Substance abuse treatment is vital in reducing the number of drug overdose deaths in the U.S. As of 2018, the state of California had the largest number of substance abuse treatment facilities in the U.S. However, many states in the U.S. have less than 100 substance abuse treatment facilities. Unsurprisingly, a recent survey indicated that a majority of U.S. adults thought there were not enough affordable and accessible substance abuse treatment facilities in the U.S.

Number of drug overdose deaths in the U.S. from 1999 to 2018, by gender

Exclusive Premium statistic

You need a Single Account for unlimited access.

  • Full access to 1m statistics

  • Incl. source references

  • Available to download in PNG, PDF, XLS format

Single Account

$39 $59 per month *
in the first 12 months
33% discount until March 31st
*Duration: 12 months, billed annually, single license

Access to this and all other statistics on 80,000 topics from

$468 / Year
$708 / Year

Show detailed source information?
Register for free
Already a member?
Log in

Release date



United States

Survey time period

1999 to 2018

Supplementary notes

Opioids—primarily prescription pain relievers and heroin—are the main driver of overdose deaths.

Statista Accounts: Access All Statistics. Starting from $468 / Year
Basic Account
Get to know the platform

You only have access to basic statistics.
This statistic is not included in your account.

Single Account
The ideal entry-level account for individual users
  • Instant access to 1m statistics
  • Download in XLS, PDF & PNG format
  • Detailed references
$59 $39 / Month *
in the first 12 months
Corporate Account
Full access

Corporate solution including all features.

* Prices do not include sales tax.

Statistics on "Drug use in the U.S."

Statista Accounts: Access All Statistics. Starting from $468 / Year
Learn more about how Statista can support your business.