Top antidepressant drugs in the United States based on revenue in 2011-2012 (in million U.S. dollars)

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Revenue in million U.S. dollars
Cymbalta4,094.2
Lexapro2,107.1
Escitalopram oxalate650.3
Pristiq555.7
Bupropion hydrochloride XL379.1
Venlafaxine hydrochloride ER283.7
Effexor XR208.3
Wellbutrin XL184.1
Bupropion hydrochloride SR169.8
Sertraline hydrochloride121
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About This Statistic

This statistic represents the top antidepressant drugs in the United States, based on revenue between July 2011 and June 2012. In this period, antidepressant Cymbalta generated around 4.1 billion U.S. dollars of revenues.


Antidepressant drugs market

There is a wide range of antidepressant drugs and drugs used to augment antidepressants, which target different aspects of the chemical function within the body. Cymbalta and Lexapro are among the top antidepressants in the United States based on revenue. Cymbalta is a trade name for the drug Duloxetine, a serotonin-norepinephrine reuptake inhibitor manufactured and marketed by Eli Lilly. Duloxetine can also be used for osteoarthritis and musculoskeletal pains. Escitalopram, known under the brand name Lexapro, is a selective serotonin reuptake inhibitor taken to treat major depressive disorder and general anxiety disorders in adults and those over 12 years old. By prescription, citalopram hydrobromide, another type of selective serotonin reuptake inhibitor, was among the top antidepressant drugs in the United States in 2011-2012 with over 39 million prescriptions.

Iceland is among the world’s highest consumer of antidepressants as of 2011, with 106 out of every 1,000 people using antidepressants. Among high school students in the United States, 41.4 percent of Hispanic females reported feeling sad or hopeless to the point where they have stopped doing some of their normal activities, while 18 percent of Black (non-Hispanic) males reported similar emotions based on a survey in 2011.

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