Top 15 pharmaceutical products by sales worldwide in 2016 (in million U.S. dollars)

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Sales in million U.S. dollars
Humira 16,078
Enbrel 8,874
Prevnar 135,718

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This statistic illustrates the top 15 pharmaceutical products by sales worldwide in 2016. In that year, GlaxoSmithKline's pharmaceutical product Advair/Seretide was ranked 15th, with global sales of some 4.3 billion U.S. dollars. The top product was Abbvie's Humira, generating more than 16 billion dollars. Humira is a drug used for especially for the treatment of rheumatoid arthritis.
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Release date
March 2017
Survey time period
Supplementary notes
One top-selling drug could not be ranked and included in this list. Eliquis (apixaban) is co-marketed by Bristol-Myers Squibb (BMS) and Pfizer, but sales figures are only available from BMS ($3.343 billion in 2016). Pfizer combines sales figures for Eliquis and other products co-developed with partner companies in an “Alliance revenues” reporting line that stood at $1.588 billion last year. Pfizer says that line consists “primarily” of Eliquis, without furnishing a specific figure.

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