
U.S. drug overdose age-adjusted death rates from 1999 to 2021, by gender
In 2021, the age-adjusted drug overdose death rate for males was 45.1 per 100,000 population. Opioids are the main driver of overdose deaths in the United States. This statistic presents the age-adjusted drug overdose death rate in the U.S. from 1999 to 2021, by gender, per 100,000 population.