Rare factor deficiencies patient share by gender U.S. 2022

As of 2022, around 64 percent of patients with factor II deficiencies were female, compared to 36 percent who were male. This statistic shows the distribution of patients in the U.S. with rare factor deficiencies as of 2022, by gender.

Distribution of patients in the U.S. with rare factor deficiencies as of 2022, by gender*

Characteristic	Male	Female
Factor I	43%	57%
Factor II	36%	64%
Factor V	38%	62%
Factor VII	48%	52%
Factor X	42%	58%
Factor XI	44%	56%
Factor XIII	50%	50%

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Release date

June 2022

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Region

United States

Survey time period

as of March 2022

Supplementary notes

* The HTC Population Profile contains 47 transsexual individuals. For confidentiality purposes, the number of transsexual patients is too small to report by year or other characteristics. Transsexual patients have been included in the counts of male and female according to the sex assigned to them at birth since hemophilia and von Willebrand disease, the most common congenital bleeding disorders, affect the sexes differently. On August 10, 2020, the responses for this question changed such that “Male to Female” (i.e., transsexual) and “Female to Male” were removed and “Intersex” was added. The number of intersex patients is too small to report by year or other characteristics; therefore, these counts have been excluded to protect patient confidentiality.

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