Total number of biotechnology companies in Europe 2018

* Biotechnology firms use biotechnology to produce goods or services and/or to perform biotechnology R&D. These firms are captured by biotechnology firm surveys. Biotechnology R&D firms perform biotechnology R&D. These firms are captured by R&D surveys.
For Latvia, this includes medical biotechnology, environmental biotechnology, industrial biotechnology and agricultural biotechnology.
For the United States, prior to 2017 statistics are based on companies in the United States that reported to the survey and had 5 or more employees (i.e., these statistics do not include an adjustment to the weight to account for unit nonresponse). Beginning in 2017, the survey includes companies with 10 or more employees (companies with fewer than 10 employees are included in a separate survey, the Annual Business Survey). Beginning in 2018, weights are adjusted to account for unit nonresponse and statistics are for companies that performed or funded $50,000 or more of R&D.