U.S. top10 OTC brands by revenue 2013

This statistic shows the top ten OTC (over-the-counter) brands distributed by revenue in 2013 in the United States. In that year, the list was topped by the ibuprofen brand Advil with a sales volume of approximately 490.9 million U.S. dollars.

Top OTC brands

Advil and Poise are among the top over-the-counter (OTC) drug brands in the United States, accounting for 490.9 million U.S. dollars and 379.1 million U.S. dollars in revenue, respectively, in 2013. Advil is a brand of ibuprofen, manufactured by Pfizer and is considered an anti-inflammatory drug. It is a medication that is said to offer pain relief and sold 66.6 million units in the United States in 2013. Advil was initially produced as a prescription medication for rheumatoid arthritis and made available in the nation in 1974.

OTC drugs can be sold to a customer without a physician’s prescription and are often regulated based on their active pharmaceutical ingredients. In the United States, OTC medications are regulated by the Food and Drug Administration (FDA). The FDA also monitors all OTC product advertisements. More recently, the FDA has considered making certain pharmaceutical products such as those targeted for asthma, headache, and birth control more widely available as OTC drugs. Among new therapeutic OTC products in the United States, cough and cold and allergy medication accounted for 35 percent of the nation’s share. In 2013, this medication category generated 7.7 billion U.S. dollars in the OTC market. Sleep remedies are also a common OTC category, with Vicks Nyquil ZzzQuil (liquids) generating 74.4 million U.S. dollars in revenue in 2013.

Top 10 OTC brands by revenue in the U.S. in 2013*

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Release date

March 2014


United States

Survey time period


Supplementary notes

* For total U.S. multi-outlet (supermarkets, drug, mass, military commissary, and select club and dollars stores.

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