
Rates of the leading causes of death in the U.S. 2021
Cardiovascular disease
Deaths from cardiovascular disease are more common among men than women but have decreased for both sexes over the past few decades. Coronary heart disease accounts for the highest portion of cardiovascular disease deaths in the United States, followed by stroke and high blood pressure. The states with the highest death rates from cardiovascular disease include Mississippi, Oklahoma, and Alabama. Smoking tobacco, physical inactivity, poor diet, stress, and being overweight or obese are all risk factors for developing heart disease.
Cancer
Although cancer is the second leading cause of death in the United States, like deaths from cardiovascular disease, deaths from cancer have decreased over the last few decades. The highest death rates from cancer come from lung cancer for both men and women. Breast cancer is the second deadliest cancer for women, while prostate cancer is the second deadliest cancer for men. Kentucky, West Virginia, and Mississippi lead the nation with the highest cancer death rates.