Top 50 global pharmaceutical and biotech companies by R&D intensity in 2018/2019

This statistic represents the worlds's top 50 pharmaceutical and biotechnology companies based on R&D intensity in 2018/2019. In that year, Tanvex Biopharma from Taiwan had the highest R&D intensity of over 428,000 percent. The R&D intensity is calculated from a company's R&D spending divided by the company's sales.

World's top 50 pharmaceutical and biotechnology companies based on R&D intensity in 2018/2019*

R&D intensity
Tanvex Biopharma 428,205.6%
Obseva 418,740.4%
Clearside Biomedical 227,544.1%
Nantkwest 113,655.4%
TG Therapeutics104,862.5%
Zai Lab 93,239.4%
Shanghai Junshi Bioscience 18,380.6%
Innovent Biologics 12,142.7%
Prothena 10,495.1%
Stemline Therapeutics 9,445%
Aurinia Pharmaceuticals 8,863.3%
Iterum Therapeutics 7,841.1%
Bellicum Pharma 6,252.9%
Idera Pharmaceuticals 6,220.4%
Selecta Biosciences 5,181%
Gritstone Oncology 4,530.6%
Clementia Pharmaceuticals 4,129.5%
Syndax Pharma 3,962.2%
Translate Bio 3,958%
Crispr Therapeutics 3,541.9%
Cstone Pharmaceuticals 3,515.9%
Kadmon Holdings 3,507.6%
Urogen Pharma 3,274.3%
Adverum Biotechnologies 3,010%
Hua Medicine 2,947.4%
Ardelyx 2,661%
Revance Therapeutics 2,480.6%
Syros Pharmaceuticals 2,347.9%
Medicines 2,192.1%
Ra Pharma 2,074%
Ocular 1,855%
Foamix Pharmaceuticals 1,793.4%
Proteostasis Therapeutics 1,671.5%
Xeris Pharmaceuticals 1,553.3%
Insmed 1,477.2%
Synlogic 1,409.3%
Ascendis Pharma 1,318%
Gw Pharmaceuticals 1,202.6%
Homology Medicines 1,201.5%
Abeona Therapeutics 1,197.5%
La Jolla Pharmaceutical 1,166.5%
Vbi Vaccines 1,146.6%
Zealand Pharma 1,106.2%
Achaogen 1,088.6%
Fate Therapeutics 1,081.9%
Anaptysbio 1,023.9%
Advaxis 939.6%
Corbus Pharmaceuticals Holdings 908.1%
Arbutus Biopharma 874.5%
Wave Life Sciences 832.6%
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Release date

December 2019



Survey time period

2018 and 2019

Supplementary notes

* R&D intensity = R&D expenditures divided by sales.

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